The dual benefits of population-scale genomics

Science is perpetually evolving, but certain inflection points stand out. In the 1970s, Fred Sanger and his team at the Medical Research Council Laboratory of Molecular Biology, in the United Kingdom, introduced a new method of DNA sequencing, which enabled small runs of DNA to be read in succession. The development of that technique, now known as Sanger sequencing, launched a long period of discovery. Positional cloning and other basic research techniques laid the foundation for the clinical panels that now guide diagnosis and disease management.

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